Computerised versus conventional methodology of radiographic joint destruction assessment in early rheumatoid arthritis
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چکیده
منابع مشابه
Computerised versus conventional methodology of radiographic joint destruction assessment in early rheumatoid arthritis
OBJECTIVES To compare computerised and conventional methodology of radiographic joint destruction assessment in early rheumatoid arthritis (RA). METHODS We investigated the contribution of the 3rd-to-5th carpometacarpal joints (CMC3-5, which are excluded in computerised assessment so far owing to bone overlapping) to total joint space narrowing (JSN) scores in two cohorts of patients with ear...
متن کاملRadiographic joint destruction in postmenopausal rheumatoid arthritis is strongly associated with generalised osteoporosis.
OBJECTIVES To investigate determinants of joint destruction and reduced bone mineral density (BMD) in postmenopausal women with active rheumatoid arthritis (RA) not treated with bisphosphonates or hormone replacement therapy and to evaluate if there are common markers of erosive disease and bone loss. METHODS BMD was measured using dual x ray absorptiometry and joint damage was examined by x ...
متن کاملAnti-type II collagen antibodies are associated with early radiographic destruction in rheumatoid arthritis
INTRODUCTION We have previously reported that high levels of antibodies specific for native human type II collagen (anti-CII) at the time of RA diagnosis were associated with concurrent but not later signs of inflammation. This was associated with CII/anti-CII immune complex (IC)-induced production of pro-inflammatory cytokines in vitro. In contrast, anti-cyclic citrullinated peptide antibodies...
متن کاملGene therapy in rheumatoid arthritis: how to target joint destruction?
Received: 7 September 1999 Revisions requested: 20 September 1999 Revisions received: 23 September 1999 Accepted: 23 September 1999 Published: 26 October 1999 © Current Science Ltd Important note about how to cite this article This article is also available online in the Arthritis Research website. To avoid confusion, please ensure that only the online version of the article is cited in any ref...
متن کاملJoint Destruction in Rheumatoid Arthritis: Experimental, Clinical and Epidemiological Studies
Background. Rheumatoid arthritis (RA) is a common autoimmune disease characterized by chronic polyarticular synovial inflammation. Erosive joint destruction represents a major unsolved complication of RA. Objectives. The aim of this thesis was to obtain increased knowledge of joint destruction by using a multidisciplinary approach. Firstly, the pathophysiological background of joint destruction...
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ژورنال
عنوان ژورنال: RMD Open
سال: 2015
ISSN: 2056-5933
DOI: 10.1136/rmdopen-2015-000148